POMARES, José; PALOMINO R, Roberto; GOMEZ, Claudio J    GOMEZ‑CAMARGO, Doris. Metabolic Syndrome and Perioperative Complications During Elective Surgery Using General Anesthesia. []. , 40, 2, pp.106-112. ISSN 0120-3347.  https://doi.org/10.1016/S0120-3347(12)70022-9.

Introduction: Metabolic Syndrome (MS) is a cluster of alterations associated to high risk of cardiovascular diseases and diabetes mellitus. Although Metabolic Syndrome is a public health issue, little has been studied about its impact in the anesthetic-surgical scene. Aims: To analyze the correlation level between MS and perioperative complications, in patients under programmed surgery with general anesthesia technique in Cartagena, Colombia. Materials and methods: A case control study was designed, where 300 patients were enrolled: 150 cases and 150 controls. Socio-demographic, hemodynamics and respiratory variables, as well as surgical complications (hypotension, hypertension, hypoxemia, bleeding, moderated-severe pain and post chirurgical nausea-vomiting) were registered. Fisher’s exact test and X2, where appropriated were employed to compare categorical data. A logistic regression model was applied to calculate correlation between variables. Results: Surgical complications were more frequent in cases group (P<.001). Differences in age and ASA physical status were also found (P<.05). MS was correlated to perioperative complications (OR: 3.31; P<.05). ASA III physical status was another risk factor to post chirurgical complications development (OR: 4.01; P<.05). None mortality case was reported. Conclusions: In a comparison with healthy population, Metabolic Syndrome represented a risk factor to perioperative complications development. According to results, further prevention and approach guidelines in order to reduce perioperative complications associated to Metabolic Syndrome.

: Insulin resistance; General anesthesia; Medicine; Cardiovascular diseases.

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