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Revista colombiana de Gastroenterología
Print version ISSN 0120-9957On-line version ISSN 2500-7440
Abstract
RUIZ-BARRIOS, Judith; RODRIGUEZ-ARRIETA, Hernán and DIAZ-MONTES, Yennifer. Primary Signet Ring Cell Carcinoma of the Duodenum: Case Report. Rev. colomb. Gastroenterol. [online]. 2023, vol.38, n.3, pp.355-358. Epub Jan 18, 2024. ISSN 0120-9957. https://doi.org/10.22516/25007440.947.
Introduction:
Primary carcinoma of the duodenum is an infrequent malignancy; it represents 0.3-0.5% of all carcinomas of the GI tract and 33-45% of all carcinomas of the small intestine.
Clinical case:
A 57-year-old female patient with nonspecific GI symptoms and unintentional weight loss was diagnosed with diffuse, infiltrating, and ulcerated adenocarcinoma in the duodenum. Surgical management with duodenopancreatectomy was considered; however, it could not be performed due to deteriorating nutritional status. She later died due to abdominal sepsis.
Conclusion:
The clinical manifestations of adenocarcinoma of the duodenum are variable and nonspecific. It is a challenge to make an early diagnosis. We recommend considering the diagnostic possibility in patients with nausea, emesis, abdominal pain, and weight loss, which requires esophagogastroduodenoscopy and histological and immunohistochemical confirmation.
Keywords : Neoplasm; duodenum; mucinous adenocarcinoma.