Abstract

ACEVEDO, German A; VEGA, Agustín  and  RIBON, Wellman. Multidrug-resistant tuberculosis. Rev. Univ. Ind. Santander. Salud [online]. 2013, vol.45, n.3, pp.87-92. ISSN 0121-0807.

Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis. In 2010, there were 8.8 million incident cases in the world, and, in recent years, populations of mycobacteria with resistance to first-line drugs have emerged. The resistance to rifampin and isoniazid has been defined as multidrugresistant tuberculosis (TB MDR). TB MDR has an incidence of approximately 3.6% in the world. This review will focus on the current stage TB MDR in the world, including a regional analysis of Colombian cases. It will discuss the mechanism of resistance of the microorganism, genes involved, and the risk factors associated with the generation of resistance in some communities

Keywords : Tuberculosis; multidrug-resistant tuberculosis; risk factors.

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