Abstract

TIBADUIZA MOGOLLON, Yuriet Alexandra  and  MIRANDA DIAZ, Audrey José. Extrapyramidal Side Effects of Antiemetics. Rev. Med [online]. 2019, vol.27, n.2, pp.63-72.  Epub Nov 26, 2022. ISSN 0121-5256.  https://doi.org/10.18359/rmed.3658.

Antiemetics are frequently used by various areas of medicine, although there is a tendency to underestimate their neurological adverse effects. This paper aims to review the literature on the physiology, pharmacology, predisposing factors, clinical picture, and management of the extrapyramidal side effects of antiemetics. Scientific journal articles, books, and dissertations were searched. The search engines Medline, LILACS, PubMed, EMBASE, Current Contents, and Google Scholar were used with the following keywords: dehydration, gastroenteritis, vomit, antiemetics, dystonia, dopamine, hyperthermia, cytochrome, metoclopramide, and domperidone. Two hundred and fifty-two articles were obtained, 50 of which were considered suitable for review. From the analysis, it was concluded that antiemetics are often used by general medicine and specialties such as anesthesiology and pediatrics; therefore, knowledge of the extrapyramidal effects will allow early diagnosis and treatment.

Keywords : Gastroenteritis; vomit; antiemetics; dystonia.

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