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Urología Colombiana
On-line version ISSN 2027-0119
Abstract
GALVIS, Juan C. et al. The role of PET-PSMA in guiding prostate cancer radiation therapy: experience in a salvage and curative setting. Urol. Colomb. [online]. 2023, vol.32, n.2, pp.36-44. Epub Apr 25, 2024. ISSN 2027-0119. https://doi.org/10.24875/ruc.23000005.
Introduction:
The role of positron emission tomography (PET) prostate-specific membrane antigen (PSMA) in guiding radiation therapy treatment plans remains to be defined.
Methods:
We conducted a retrospective observational study of patients with prostate cancer referred for radiotherapy. Our objective was to establish the role of PET-PSMA in decision-making and changes in the radiotherapy treatment plan.
Results:
In the entire cohort, 26.8% had lymph node involvement outside the conventional field. The PET results upstaged and changed radiotherapy treatment plans for 75% in primary radiotherapy and 50% in salvage radiation.
Conclusions:
PET-PSMA changes decision-making and treatment planning for radiotherapy, including treatment volumes not traditionally delimited in contour atlases.
Keywords : Radiation; Radionuclide imaging; Prostate cancer; Prostate-specific membrane antigen; Positron emission tomography/Computerized tomography.
