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Biomédica
Print version ISSN 0120-4157On-line version ISSN 2590-7379
Abstract
MEDINA-VALENCIA, Diego et al. Impact of health-related quality of life on pediatric patients who underwent hematopoietic stem cell transplantation in a Colombian institution. Biomed. [online]. 2022, vol.42, n.3, pp.531-540. Epub Sep 02, 2022. ISSN 0120-4157. https://doi.org/10.7705/biomedica.6403.
Introduction:
Hematopoietic stem cell transplantation is the curative option for some diseases and is increasing patient survival. The health-related quality of life in these patients is not systematically evaluated.
Objectives:
The present study sought to describe the health-related quality of life and complications in children who underwent hematopoietic stem cell transplantation.
Materials and methods:
A cross-sectional study was conducted on pediatric transplanted survivors. Health-related quality of life was measured using the KIDSCREEN-27 scale and Short Form-12 (SF-12) in patients between 8 and 14 years of age and those over 14 years, respectively. Statistical analysis was performed using STATA 12 software. We used the Rasch model person parameter estimates translated into T-values to score the questionnaire.
Results:
A total of 42 children answered the questionnaires. The most frequent adverse events were chronic graft Vs. host disease and endocrine complications. According to European norm data in the KIDSCREEN-12 scale, scores for the school dimension and social and peer support were below the 50th. percentile. The group administered immunosuppressants had lower scores on the physical component of the SF-12™ scale.
Conclusions:
In general, the KIDSCREEN-27 does appear to suggest some quality-of-life deficit in younger children. The scales showed reliability in this population.
Keywords : Bone marrow transplantation; quality of life; child; mental health.