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Revista Colombiana de Reumatología
Print version ISSN 0121-8123
Abstract
SEBASTIAN SEBASTIAN, Cristina et al. Pancreatitis with bone infarctions and panniculitis, is this really the PPP (pancreatitis, panniculitis, polyarthritis) syndrome? Presentation of 2 clinical cases and literature review. Rev.Colomb.Reumatol. [online]. 2015, vol.22, n.4, pp.234-238. ISSN 0121-8123. https://doi.org/10.1016/j.rcreu.2015.10.004.
The pancreatitis, panniculitis and polyarthritis syndrome (PPP) is mainly caused by systemic release of pancreatic enzymes to the blood stream that cause inflammation of subcutaneous tissue (primary panniculitis) and periarticular space (arthritis). It is less commonly associated with bone marrow involvement. We showed two patients with PPP syndrome with clinical arthritis, extensive bone infarctions, and contiguous panniculitis. A literature review found very few cases evaluated by magnetic resonance. In our analysed cases the arthritis syndrome was associated with bone infarctions and avascular necrosis. Extensive bone necrosis can produce disruption of cortical bone and secondary panniculitis, making it difficult to distinguish from arthritis.
Keywords : Pancreatitis; panniculitis and polyarthritis syndrome Pancreatitis; Panniculitis; Polyarthritis; Bone infarcts; Magnetic resonance imaging.