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Revista Colombiana de Reumatología
Print version ISSN 0121-8123
Abstract
ROVERANO, Susana; CALVO, Romina; ORTIZ, Alberto and PAIRA, Sergio. Rheumatic manifestations associated with cocaine addiction. Rev.Colomb.Reumatol. [online]. 2020, vol.27, n.4, pp.286-290. Epub Aug 15, 2021. ISSN 0121-8123. https://doi.org/10.1016/j.rcreu.2019.01.006.
Cocaine use is associated with several rheumatic syndromes. A series of cases is presented of 10 patients (7 male and 3 female), age at onset: 19-38 years-old. They consulted due to a variety of symptoms: fever, arthritis, swollen hands, stroke, fetal losses, arterial hypertension, alveolar hemorrhage, leucocytoclastic vasculitis, genital bleeding, among others. Half of them showed positive ANA and Ro antibodies, lymphopenia and positive P-ANCA. Treatments with steroids in bolus, cyclophosphamide and rituximab were used, with a good response. This series highlights clinical manifestations at onset that can mimic primary rheumatic diseases. Rheumatologists should consider cocaine use in the differential diagnoses of vasculitis and pseudovasculitis syndromes.
Keywords : Vasculitis; Cocaine; Purpura.