Abstract

GAVIRIA, Lina María; CARDENAS, Beatriz; MONDRAGON, María Cecilia  and  GUEVARA, Natalia María. IgD secretory plasma cell myeloma, a diagnostic challenge. Acta Med Colomb [online]. 2013, vol.38, n.4, pp.268-272. ISSN 0120-2448.

Abstract IgD secretory plasma cell myeloma is a rare and aggressive plasma cell neoplasm which usually affects younger individuals than other myelomas. Diagnosis is difficult since there is no monoclonal protein spike, characteristic of myelomas; however, immunofixation, IgD quantification and urine tests are useful for its diagnosis. With regard to clinical manifestations, anemia, renal failure and multiple bone lesions are frequent. In addition, the disease has an aggressive course with poor response to conventional chemotherapy. Here is reported a case of a 57 year old woman with a history of bone pain and multiple lytic bone lesions who was diagnosed with IgD secretory myeloma through serum protein electrophoresis, immunofixation in serum and urine, IgD quantification and medullary study. (Acta Med Colomb 2013; 38: 268-272).

Keywords : multiple myeloma; immunoglobulin D; renal failure.

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