Abstract

CUCA SUAREZ, Luis Enrique  and  BANOL VARGAS, Óscar Eliécer. NEW CHALCONES FROM Beilschmiedia tovarensis. Rev.Colomb.Quim. [online]. 2005, vol.34, n.1, pp.35-41. ISSN 0120-2804.

Two new chalcones: 2’, 6’-dihydroxy-4-isopenteniloxy-3,4(3’’ ’,3’’ ’-dimethylpyrano) chalcone and 4,2’, 6’- trihydroxy-3’,4’-metilenodioxo-3-isopentenilchalcone were isolated from the wood ethanolic extract of Beilschmiedia tovarensis. Isolation was performed by chromatographic techniques. The elucidation of the structure of the compounds was accomplished by spectroscopic techniques (IR, NMR-¹H, ¹³C and MS). Also, the crude wood extract was tested in vitro for biological activity, having significant results for antimicrobial activity in Gram (+) stumps: Sataphylococcus aureus and Enterococcus faecalis. Test of antimalarial and antituberculosis activities gave negative results.

Keywords : Lauraceae; Beilschmiedia tovarensis; chalcona; antimicrobial activity.

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