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Acta Neurológica Colombiana
Print version ISSN 0120-8748On-line version ISSN 2422-4022
Abstract
RENTERIA-ROA, Jairo Andrés; SUAREZ-ACOSTA, Carolina del Rosario; PELAEZ-ARROYAVE, Luis Guillermo and PALACIO-SANCHEZ, Andrés Felipe. Acute stroke in young woman with coronavirus disease 19 and no cardiovascular risk factor: case report. Acta Neurol Colomb. [online]. 2023, vol.39, n.1, pp.33-38. Epub Apr 05, 2023. ISSN 0120-8748. https://doi.org/10.22379/24224022440.
INTRODUCTION:
It is known that COVID-19 is associated with venous and arterial thromboembolic events in patients with history of hypertension and atherosclerosis. Herein, it is presented a case of a young woman without known cardiovascular risk, who was infected by SARS-COV 2 and then an ischemic stroke.
CASE:
44 years-old woman with moderate COVID-19 in protocolary treatment with anticoagulants, steroid and oxygen. In the seventh day since symptoms onset, she presented acute ischemic stroke due to acute thrombosis of right carotid artery, and right and left medial cerebral arteries, then rapidly developed malignant cerebral edema and brain death. Vascular study failed to report and etiology other than COVID-19.
DISCUSSION:
It is suggested that the infection produces a systemic inflammatory state, endothelialitis, ulceration of preexisting atherosclerotic plaques, and hypercoagulability that facilitate thrombosis. Ischemic stroke is described in 1 to 5% of COVID-19, it is common to find an elevation of acute phase reactants and products of fibrin metabolism. Multiple vascular territories are usually compromised in patients with known cardiovascular risk factors and 12 days after the onset of symptoms.
CONCLUSION:
COVID-19 by itself is a risk factor for arterial thrombosis secondary to systemic infection and hypercoagulability states and it should be taken into account in the study of ischemic stroke in young patients.
Keywords : COVID-19; Stroke; Brain Death; Thrombosis (MeSH).