Abstract

CALDERON-VELEZ, Juan Camilo. Iron supplementation and oxidative stress in pregnancy: a little-discussed paradox. Rev Colomb Obstet Ginecol [online]. 2007, vol.58, n.4, pp.304-308. ISSN 0034-7434.

Providing iron supplement during pregnancy is a widely accepted medical practice. However, iron is involved in initiation and propagation chain reactions producing reactive oxygen species and lipid hydroperoxides, in turn playing an important role in the pathophysiology of gestational diabetes and preeclampsia. A paradox is then faced; iron supplement can reduce the risk of anaemia and anaemia-related complications but it can promote other diseases developing. Such paradox is discussed and some studies are suggested which could be carried out to clarify when iron supplement may be indicated and used in the safest conditions for pregnant women.

Keywords : iron; free radicals; anaemia; pregnancy.

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