Services on Demand
Journal
Article
Indicators
Cited by SciELO
Access statistics
Related links
Cited by Google
Similars in SciELO
Similars in Google
Share
Revista Colombiana de Ciencias Pecuarias
Print version ISSN 0120-0690On-line version ISSN 2256-2958
Abstract
GRUBMAN, Marvin J. New approaches to control foot-and-mouth disease: antivirals and novel vaccines. Rev Colom Cienc Pecua [online]. 2006, vol.19, n.3, pp.341-346. ISSN 0120-0690.
Foot and mouth disease (FMD) is a highly contagious viral-induced disease of cloven-hoofed animals that results in serious economic consequences in affected countries that have a significant international livestock trade. Currently disease control measures include inhibition of susceptible animal movement, slaughter of infected and susceptible in-contact animals, disinfection, and possibly vaccination with an inactivated whole virus antigen. However, there are a number of problems with use of the current vaccine in outbreaks in countries which have been previously free of FMD. As a result countries which vaccinate face a longer delay in regaining FMD-free status than countries which do not vaccinate but rather slaughter all infected or susceptible in-contact animals. Researchers have been attempting to develop both new FMD vaccines to overcome the limitations of the current inactivated vaccine as well as methods to more rapidly induce a protective response. In this manuscript I discuss the most effective new FMD vaccines and novel antiviral strategies that are currently being examined.
Keywords : antiviral strategies; foot and mouth disease; prevention, vaccines.