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ORINOQUIA
On-line version ISSN 0121-3709
Abstract
MONICAA., Vásquez-Piñeros; IANG S., Rondón-Barragan and PEDRO R., Eslava-Mocha. Imunoestimulantes em teleósteos: Probióticos,Beta-glucanas e LPS. Orinoquia [online]. 2012, vol.16, n.1, pp.46-62. ISSN 0121-3709.
Immunostimulants mainly consist ofmicroorganisms’ structural elements whose principle is based on stimulating theinnate immune system, leading to an improvement in animals’ sanitary state andincreased resistance to pathogens. Β-glucans and lipopolysaccharides are some of the most used immunostimulants in the fish industry, includingbeneficial bacteria called probiotics. Studies on fish have been focused on the in vitro and in vivo evaluation of cellular and humoralresponses, modulating gene transcription and the effects of resistanceregarding pathogens of interest, usually having positive effects on the fishes’immunological state and resistance to disease. The proposed review was aimed atinvestigating the mechanisms of action of some of the most usedimmunostimulants, conceptualising their use in aquiculture and discussingrecent work on the topic thereby forming the basis for proposing pertinent,feasible investigations for tackling some problems in the fish-farminghealth/sanitation area.
Keywords : peces; aquiculture; disease; fish; health/sanitation; immune system.