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Revista Colombiana de Cardiología
Print version ISSN 0120-5633
Abstract
CARRERA, Tito A.; JAIMES, Claudia and RODRIGUEZ, Diego. Giant cell myocarditis. Rev. Colomb. Cardiol. [online]. 2016, vol.23, n.5, pp.410-416. Epub May 02, 2016. ISSN 0120-5633. https://doi.org/10.1016/j.rccar.2016.02.006.
Giant cell myocarditis is a rare condition with a great impact with regards to mortality of otherwise young and healthy patients, causing multiple clinical presentations, such as heart failure, refractory ventricular arrhythmias and blocks. Its diagnosis is reached with a high degree of suspicion and with the confirmation by means of a endomyocardial biopsy with the presence of multinucleated giant cells without a granulomatous pattern. Its immunomodulatory treatment has considerably changed during the last years, with a clear reduction in mortality rates, though complementary management strategies are still required, such as the use of intracardiac devices and/or heart transplantation in order to achieve better longterm results.
Keywords : Giant cell; myocarditis; Heart failure; Ventricular; arrhythmias; Mortality; Cardiac sarcoidosis.