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Revista Colombiana de Cardiología
Print version ISSN 0120-5633
Abstract
VILLAMIZAR, Alonso Merchán et al. Achievement of LDL cholesterol targets in patients with coronary artery disease. Rev. Colomb. Cardiol. [online]. 2020, vol.27, n.6, pp.511-516. Epub July 22, 2021. ISSN 0120-5633. https://doi.org/10.1016/j.rccar.2019.10.004.
Introduction:
Patients with established atherosclerotic disease require treatment with statins in order to reduce the probability of new events.
Objective:
To identify the percentage of patients with established atherosclerotic coronary disease that achieve cLDL (LDL - cholesterol) levels less than 70mg/dL, and to describe its distribution in three treatment groups: statins, other lipid lowering drugs, and without treatment.
Methods:
A cross-sectional, descriptive observational study was conducted on patients diagnosed with atherosclerotic disease from 2017 and over 18-years-old from 3 tertiary hospitals. A record was made of the lipid profile that was performed at least three months after the diagnosis.
Results:
A total of 746 patients with atherosclerotic coronary disease were included. The mean age was 65.3±10.9 years and the majority (75.5%) were males. Of the total number of patients evaluated, 97.8% were prescribed a therapy with at least one statin, 0.7% with other lipid-lowering drugs, and 1.5% had no treatment. Just over half (56%) of the patients had cLDL levels of less than 70mg/dL.
Conclusions:
The widespread use of clinical practice guidelines for dyslipidaemias in adults in Colombia, and the incorporation of high-intensity statins, has led to an improvement in the proportion of patients with established atherosclerotic disease achieving cLDL targets. However, a high percentage still does not reach the targets, which suggests a need for an improving of the use of available and recently developed therapies.
Keywords : Statins; Lipid profile targets; Atherosclerotic cardiovascular disease; LDL-Cholesterol.