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Revista Colombiana de Cardiología
Print version ISSN 0120-5633
Abstract
RAMOS-JIMENEZ, Javier; SANCHEZ-VEGA, Juan D. and ZAMORANO-GOMEZ, José L.. Sex-related risk of arrhythmia in takotsubo syndrome. Rev. Colomb. Cardiol. [online]. 2022, vol.29, n.2, pp.226-230. Epub May 19, 2022. ISSN 0120-5633. https://doi.org/10.24875/rccar.m22000141.
Takotsubo syndrome, also known as stress cardiomyopathy, is a difficult diagnostic challenge as, in many cases, its presentation can overlap with that of myocardial infarction due to plaque rupture. The definitive diagnosis is based on the lack of culprit lesions on coronariography. The pathophysiology of the disease has not been completely ascertained, and it has a generally benign prognosis. However, a not inconsiderable percentage of patients experience serious complications, notably malignant arrhythmias like polymorphic ventricular tachycardia due to a prolonged QT interval. Despite takotsubo syndrome affecting mainly women who, furthermore, generally have longer basal QT intervals, sudden death due to arrhythmias is more common in men with this disease. Two cases are presented of extremely prolonged corrected QT intervals in patients with takotsubo, with different outcomes. The purpose of this paper is to highlight and review the electrocardiographic and prognostic differences related to the gender of the individuals who develop this controversial disease.
Keywords : Takotsubo; Stress cardiomyopathy; Torsade de pointes; QT interval; Ventricular tachycardia.