Abstract

FLOREZ-CARDONA, José Alejandro et al. Prevalence of carotid disease in a tertiary hospital care in Mexico City, Mexico. Acta Neurol Colomb. [online]. 2012, vol.28, n.4, pp.187-193. ISSN 0120-8748.

Introduction: carotid atherosclerotic disease (CAD) is cause of about 15% of acute strokes. Its prevalence could be high in the Latin American population, but this information, in general, is largely unknown. Objetive: to describe the prevalence, severity and risk factors of CAD in a Mexican population from a third-level referral center. Materials and Methods: a total of 545 clinical records of patients who received carotid ultrasound in a period of 23 months were reviewed. We analyzed the prevalence and severity of CAD, and compared risk factors between patients with and without this condition. Results: the general prevalence of CAD was 54.7% (95% confidence interval: 50.5% to 58.8%): mild 48% and moderate-severe 7%. The most frequent risk factors were hypertension (64.8%, moderate-severe CAD: 86.8%), hypercholesterolemia (47.5%, moderate-severe CAD: 60.5%) and diabetes mellitus (40%, moderate-severe CAD: 44.7%). Twenty nine percent of patients had history of cerebral infarction. Most patients received statins and/or fibrates (68.3%, moderate-severe CAD: 86.8%), antiplatelets (62%, moderate-severe CAD: 86.8%) and angiotensin-converting enzyme inhibitors (42.8%, moderate-severe CAD: 71.1%). Among the 38 patients with moderate-severe CAD, 13 (34.2%) received carotid revascularization (12 endarterectomy and 1 angioplasty plus stenting). Conclusion: the prevalence of CAD in this Mexican population is similar to that reported in other countries. Most patients are treated conservatively. Emphasis should be made on optimal control of cardiovascular risk factors associated with CAD.

Keywords : Carotid Stenosis; Diabetes Mellitus; Dyslipidemia; Hypertension.

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