Abstract

GALLO, Gloria; RODRIGUEZ, Lucrecia; MALAVER, Diana  and  ZAPATA, Tatiana. Study of the effect of ingesting a single dose of two aromatase inhibitors on sex hormone profile of healthy volunteers. Rev. colomb. cienc. quim. farm. [online]. 2012, vol.41, n.1, pp.67-80. ISSN 0034-7418.

This work aims to study the hormonal profile changes induced by Attitude^®, dietary supplement used by athletes to increase endogenous testosterone levels by inhibiting its metabolism and subsequent transformation into estradiol. Although this product is now discontinued in the United States, It has have detected some adverse analytical findings that revealed that Colombian athletes consume this product. To achieve our objective we performed a study of two male volunteers, to evaluate their hormonal profile before and compare after of the intake. Furthermore analytical techniques were developed to detect the components of Attitude^®.

Keywords : ,4,6-androstatrien-3,17-dione (ATD) y 3-hydroxy-4-androsten-6,17-dione (3-OHAT); aromatase inhibitors; hormonal profile; testosterone.

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