Aim:

To evaluate the drug profile concerning occurrence of the polypharmacy, potential drug-drug interactions and potentially inappropriate medication prescribed to aging adults admitted for bone fractures. Cross-sectional, quantitative and analytical study, conducted in January 2019 to January of 2020 with patients attended for bone fractures in any body segment, candidates for surgical treatment, under drug therapy in the Hospital Municipal de Imperatriz (HMI), Maranhão.

Methodology:

The prescriptions were analyzed with the assistance of Lexi-Interact" database to verification potential drug-drug interactions and the Beers criteria updated in 2019 by the American Geriatrics Society to classify potentially inappropriate medications. The chi-square test and Fisher's exact test were used to verify associations.

Results:

A total of 29 geriatric patients were included in this study. The prevalence of polypharmacy was 75.8%. 25 patients (86.2%) used at least one medication potentially inappropriate for the aging adults. Of the 115 potential drug-drug interactions, 45.3% had a deleterious effect on the patient clinical condition.

Conclusion:

The frequency of polypharmacy, potential drug interactions with deleterious action on clinical condition, and prescription of potentially inappropriate medications for geriatric patients during hospitalization was high. The most prevalent pharmacological classes were NSAIDs, analgesic, antibiotic, and gastric protector. Proximal femur fractures were the most prevalent in this research. Thus, it is hoped to contribute to taking consensus measures for prescribing in this population.