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Revista Colombiana de Ciencias Químico - Farmacéuticas
Print version ISSN 0034-7418On-line version ISSN 1909-6356
Abstract
BEZERRA, Raquel Vieira et al. Evaluation of the antibacterial activity of monoterpene (r)-(+)-citronellal against Pseudomonas aeruginosa strains. Rev. colomb. cienc. quim. farm. [online]. 2022, vol.51, n.2, pp.691-702. Epub Dec 19, 2023. ISSN 0034-7418. https://doi.org/10.15446/rcciquifa.v51n2.98879.
Introduction:
Monoterpenes, which are the main constituents of most essential oils, comprise a wide range of natural and/or synthetic substances that have already exhibited diverse biological activities.
Objective:
The present study aimed to evaluate the antibacterial activity of monoterpene (R)-(+)-citronellal against Pseudomonas aeruginosa strains.
Methodology:
The serial dilution technique was used to determine the Minimum Inhibitory Concentration (MIC) and the Minimal Bactericidal Concentration (CBM) of (R)-(+)-citronellal was also determined.
Results:
The results obtained for the tested monoterpene were MIC50 equal to 512 µg/mL, thus presenting a strong antibacterial effect and CBM ranging from 512 to 1024 µg/mL, thus being considered bactericidal.
Conclusion :
Thus, it is concluded that the monoterpene (R)-(+)-citronellal, due to its antimicrobial potential, can be considered very important for the treatment of several diseases caused by Pseudomonas aeruginosa.
Keywords : Terpene; Phytotherapy; Antibacterial activity.