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Revista Colombiana de Ciencias Químico - Farmacéuticas
Print version ISSN 0034-7418On-line version ISSN 1909-6356
Abstract
ROCCO, Laryssa Cruz; IKEDA, Nathalya Soken; MULLER, Karla de Toledo C. and MIRANDAI, Marla Ribeiro A.. Evaluation of the physicochemical quality parameters of cream-gels based on hyaluronic acid purchased in compounding pharmacies in the city of Campo Grande-MS. Rev. colomb. cienc. quim. farm. [online]. 2022, vol.51, n.3, pp.1049-1064. Epub Mar 29, 2023. ISSN 0034-7418. https://doi.org/10.15446/rcciquifa.v51n3.100051.
Introduction:
Over the years, the search for improving self-care has extended to compound pharmacy, where the cosmetic can be manipulated according to the preferences of each person. Thus, it is necessary to provide stability for each product handled, ensuring that a safe and effective cosmetic will be dispensed. Hyaluronic acid is an active that has become popular due to its ability to maintain skin elasticity and exert a moisturizing function, in addition to acting in the reduction of fine lines.
Aim:
To analyze the quality of cosmetics manipulated with the active ingredient of Hyaluronic Acid from different compound pharmacies in the city of Campo Grande-MS, through physical-chemical laboratory analysis and labeling.
Material and methods:
Four samples of 5% hyaluronic acid-based cream-gel were acquired from master pharmacies, and the following quality control analyzes were carried out: organoleptic analysis, pH determination, density, centrifuge test, spreadability and labeling analysis.
Results:
Regarding the analyses, the results obtained were satisfactory. The organoleptic analysis, the centrifugation test and the spreadability were within the stipulated standards; however, the density test stands out, in which two samples obtained results below the stipulated; and for label analysis, no product contained a list of formulation components.
Conclusion:
At the end of the analyses, it can be pointed out that the products presented satisfactory performance in most of the proposed tests and are a safe option, of good quality and accessible to the public.
Keywords : Manipulation; quality warranty; cosmetic; stability; self-care.