Abstract

GOMEZ-RIOS, Ana C.; CARRILLO-ROZO, Mauricio E.  and  RODRIGUEZ-ORTIZ, Jorge A.. Maternal and perinatal morbidity and mortality in patients with HIV infection at Hospital Simón Bolívar, 2003-2011, Bogotá (Colombia). Rev Colomb Obstet Ginecol [online]. 2014, vol.65, n.4, pp.308-316. ISSN 0034-7434.  https://doi.org/10.18597/rcog.34.

Objective: To describe maternal and perinatal HIV-associated morbidity and mortality at Simón Bolívar Hospital between 2003 and 2011. Materials and methods: A descriptive historical cohort study. The study included pregnant women with a confirmed diagnosis of HIV infection attending prenatal control visits and receiving care during delivery and the postpartum period, between January 2003 and December 2011 at the Simon Bolívar Hospital, a general, level-III referral centre for HIV patients, located in northwest Bogota. Sampling was done consecutively and the assessment included baseline social, demographic and clinical characteristics; maternal mortality during pregnancy, at the time of delivery and during the postpartum period; and perinatal mortality. A descriptive morbidity analysis was conducted using proportions, together with an exploratory analysis of the association between the CD4 lymphocyte count and viral load, and maternal and perinatal outcomes. Results: Overall, 136 patients had a confirmed diagnosis of HIV at the institution, and complete information was obtained for 106 (78%) of them. There were no cases of maternal deaths and 2 foetal deaths in utero. The main maternal comorbidities found were anaemia (18%), STDs (22.6%), pneumonia (5.7%) and postpartum fever (4.7%). The most frequent perinatal comorbidities were low birth weight (21.7%), and seizures (2.8%). No association was found between viral load and CD4 count and maternal or perinatal morbidity. Conclusion: Pregnant women with HIV infection generally present a slight increase in maternal and perinatal complications. It is important to undertake additional studies in different population groups in order to arrive at an appropriate evaluation of all these associations.

Keywords : HIV; pregnancy; pregnancy complications; labour complications; perinatal mortality; maternal mortality.

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