Abstract

LONDONO-ARCILA, Héctor Fabio et al. DRESS syndrome induced by anticonvulsants and fulminant hepatic failure. rev.fac.med. [online]. 2017, vol.65, n.1, pp.165-168. ISSN 0120-0011.  https://doi.org/10.15446/revfacmed.v65n1.51919.

The drug rash with eosinophilia and systemic symptoms syndrome (DRESS) is a severe hypersensitive reaction induced by the use of medications. More than 100 drugs associated with this syndrome have been reported and, although most patients have a favorable clinical course, about 10% develop multiple organ failure; some cases may result in the death of the patient. This paper presents a clinical case of DRESS syndrome associated with anticonvulsive therapy that evolved to fulminant hepatic failure. The etiology, pathogenesis, clinical manifestations, diagnostic process and possible treatment of this condition are addressed.

Keywords : Anticonvulsants; Drug Hypersensitivity Syndrome; Valproic Acid; Phenytoin; Liver Failure, Acute (MeSH)..

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