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Revista Colombiana de Cardiología
Print version ISSN 0120-5633
Abstract
ECHEVERRI-MARIN, Diego A.; BETANCUR-SALAZAR, Kelly; SALDARRIAGA-GIRALDO, Clara I. and VALENCIA-DUARTE, Ana Victoria. Major adverse cardiovascular outcomes in patients with early acute coronary syndrome. Rev. Colomb. Cardiol. [online]. 2019, vol.26, n.1, pp.10-16. ISSN 0120-5633. https://doi.org/10.1016/j.rccar.2018.02.007.
Introduction and objective:
Coronary disease has become one of the main causes of death in individuals less than 55 years-old in the last 20-30 years or so. This has led to the need to increase the knowledge in this growing population, as well as its characteristics, risk factors and eventual clinical outcomes.
Methods:
A cohort study was conducted in order to evaluate the effect of the cardiovascular risk factors, as well as the clinical and coronary angiography variables on the incidence of a major adverse cardiovascular outcome, in patients with a first acute coronary event before 55 years-old. Correlations were performed between the variables and the time free from a major adverse cardiovascular outcome.
Results:
The study included 193 patients, with a mean follow-up of 1.7 years per patient. The median age was 51 years. An association was found between the type of coronary event, acute myocardial infarction with ST elevation (RR=8.4, 95% CI; 1.9-37.4) and a Killip score > II (RR 5.57, 95% CI; 1.2 - 25.2), with a greater number of in-hospital complications.
Those with circumflex artery involvement (RR=4.5, 95%CI; 1.65 - 12.4) and a requirement for three or more coronary stent implants (RR 4.7, 95%CI; 1.7-12.7), had a higher risk of suffering a new cardiovascular event.
Conclusion:
Patients less than 55 years-old with acute coronary syndrome and circumflex artery involvement, or the requirement of the implanting more than three stents, have a higher number of adverse cardiovascular outcomes.
Keywords : Acute coronary syndrome; Young adult; Coronary disease; Risk factors.