Abstract

MARTINEZ VILLOTA, Viviana Alexandra. Usefulness of anti-aquaporine-4 antibodies in the diagnosis of neuromyelitis optica. Acta Neurol Colomb. [online]. 2011, vol.27, n.3, pp.177-185. ISSN 0120-8748.

Neuromyelitis optica or Devic syndrome is a severe demyelinating syndrome. This entity although of low prevalence represents a diagnostic and therapeutic challenge, especially at the moment of differentiation with multiple sclerosis. With the discovery of aquaporin-4 specific serum autoantibody, in the pathophysiology of this syndrome, we have expanded the tools to make a diagnosis with greater certainty and identify options for treatment. Here is an update of the literature regarding its role in the diagnosis and treatment of neuromyelitis optica.

Keywords : Neuromyelitis Optica; Aquaporin-4; Aquaporin-4 Specific Serum Autoantibody; Demyelinating Diseases; Optic Neuritis; Transverse Mielitis.

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