Abstract

CONTRERAS RAMIREZ, Mónica et al. Two Case Reports of Allergies to Amino Acid Based Formula in Patients with Short Bowel Syndrome. Rev Col Gastroenterol [online]. 2016, vol.31, n.2, pp.165-168. ISSN 0120-9957.

Short bowel syndrome (SBS) is characterized by alterations in the absorption surface and in the functionality of the gastrointestinal system. Patients with SBS are more prone to allergies the protein in cow's milk and eggs. We report two cases of infants with SBS and allergic reactions to amino acid based formulas.  In the first case, the patient's response was not IgE-mediated. It manifested clinically with eosinophilic colitis that improved with the use of systemic steroids and a change to another elemental formula. In the second case, the patient initially presented intolerance to breast milk and extensively hydrolyzed formula. After feeding with the first free amino acid formula, the patient developed gastrointestinal bleeding and skin manifestations. Another free amino acid formula was substituted. The patient had transient tolerance to the new formula. Later, in the context of an unspecified viral infection with respiratory and gastrointestinal involvement, the patient presented an anaphylactic reaction to the formula which had previously been tolerated. This necessitated a change to a modular diet which was adequately tolerated. We have presented this case report because no previous reports were found in the literature about allergic reactions to basic amino acid-based formulas. There is still no consensus on the ideal formula for preventing allergic sensitization in patients with SBS

Keywords : Food allergy; short bowel syndrome; elemental formula; amino acids.

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