Abstract

OLIVEROS, Ricardo; SIERRA-PRIETO, Jonathan; BONILLA-GONZALEZ, Carlos  and  MESA-LOPEZ DE MESA, Jorge Andrés. Importance of HER2 status determination in advanced gastric cancer: A case study. Rev. colomb. Gastroenterol. [online]. 2021, vol.36, suppl.1, pp.2-10.  Epub Feb 18, 2022. ISSN 0120-9957.  https://doi.org/10.22516/25007440.503.

Advanced gastric cancer (AGC) is an entity that encompasses two distinct clinical situations: locally advanced unresectable gastric cancer and metastatic disease, with chemotherapy as the standard treatment. HER2 overexpression can occur in 9% to 38% of the cases with this disease and has been the first predictive biomarker used for trastuzumab-targeted therapy in patients with advanced gastric and gastroesophageal tumors. This article presents a patient with AGC and positive HER2 treated with conventional chemotherapy plus trastuzumab as targeted therapy with adequate clinical response.

Keywords : Advanced gastric cancer; Treatment; Trastuzumab; HER2.

        · abstract in Spanish     · text in English | Spanish     · English ( pdf ) | Spanish ( pdf )