Abstract

MESA, Juan Gonzalo  and  ARISTIZABAL, Beatriz Helena. Follow up with viral load monitoring for Epstein-Barr virus in pediatric pacients with hepatic transplant. Medicas UIS [online]. 2015, vol.28, n.3, pp.393-401. ISSN 0121-0319.  https://doi.org/10.18273/revmed.v28n3-2015015.

Introduction: Transplant patients are a challenge from every point of view. Infection with Epstein- Barr virus is common and management is often hampered by the lack of effective medicaments available. Liver transplant patients have a high incidence of Epstein-Barr virus infection / reactivation because of the the risk of primary infection during this period or immunosuppression associated reactivation. Objectives: Describe the findings when using EBV viral load monitoring in liver transplant patients in an institution of the fourth level in Medellin, Colombia. Selection of patients: Seven medical records from liver transplant patients were randomly chosen obtaining from them demographic data, cause of transplantation, time of the Epstein-Barr virus detection, viral load evolution, effects of immunosuppressive medications over them and the patient's outcome. Description of patients: Average patient age at transplant was 28,4 months, the effect of antiviral drugs (gangiclovir, valganciclovir, cytomegalovirus immunoglobulin) seems not to be adequate and sustained in decreasing viral load. Conclusions: Although the therapeutic options available for Herpes virus , as found in current literature and seen in our patients, immunosupression degree seems to be the main factor for controlling EBV replication. MÉD UIS. 2015;28(3):393-401.

Keywords : Epstein-Barr virus infections; Immunosupresion; Liver transplantation.

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