Services on Demand
Journal
Article
Indicators
Cited by SciELO
Access statistics
Related links
Cited by Google
Similars in SciELO
Similars in Google
Share
Revista de la Universidad Industrial de Santander. Salud
Print version ISSN 0121-0807On-line version ISSN 2145-8464
Abstract
BECERRA-ARIAS, Carolina; VERA-CALA, Lina M and FERNANDEZ-NINO, Julián A. Association between Tg/HDL ratio and Chronic Kidney Disease in a colombian cohort. Rev. Univ. Ind. Santander. Salud [online]. 2019, vol.51, n.4, pp.317-327. Epub Sep 26, 2019. ISSN 0121-0807. https://doi.org/10.18273/revsal.v51n4-2019005.
Introduction:
Chronic Kidney Disease (CKD) has a strong impact on global public health. This is due to the high risk of cardiovascular disease in those who suffer from it. The triglycerides / high density lipoprotein ratio has been associated with the development and progression of kidney disease.
Objective:
To estimate the association between the ratio triglycerides / high density lipoprotein and the incidence of kidney disease in a Colombian cohort.
Methodology:
Prospective cohort study of the follow-up of INEFAC 2007-2017, with 1626 participants. The main exposure was determined as a cut-off point> 3.75 in the ratio. The cases were defined as having an estimated glomerular filtration rate <60ml / min / 1.73m2 or previous medical diagnosis. Linear regression and log-binomial models were adjusted for changes in the estimated rate and incidence of chronic kidney disease. As covariates: age, sex, race, alcohol, cigarette, waist circumference, and physical activity.
Results:
The incidence of kidney disease was 0.4% (95% CI: 0.1-0.8), the average of the estimated rate was 94.3ml / min / 1.73m2. The association between the ratio triglycerides / high density lipoprotein and chronic kidney disease was not statistically significant in the unadjusted model (RR = 2.3, 95% CI: 0.5-9.4) nor in the adjusted by confounders (RR = 1.1, 95% CI: 0.2-5.6).
Conclusion:
It was not possible to determine the explored association, probably because it does not exist in the studied population or because a higher sample size is required, due to the low number of events.
Keywords : Chronic kidney disease; dyslipidemia; triglycerides; high density lipoprotein; glomerular filtration rate; incidence; association; cardiovascular disease; cohort; Colombia..