Abstract

MORA-KARAM, Claudia; CALVO-PARAMO, Enrique; QUINTERO, Eduardo Tuta  and  ARDILA, Luisa Fernanda Cardona. Bone sarcoidosis: an unusual manifestation. Rev.Colomb.Reumatol. [online]. 2022, vol.29, n.2, pp.151-154.  Epub Feb 25, 2023. ISSN 0121-8123.  https://doi.org/10.1016/j.rcreu.2020.07.001.

Sarcoidosis is a multi-system disease that involves the lung in 90% of cases. Skeletomuscular involvement of sarcoidosis may involve joints, muscles and/or bones, the latter affecting 313% of patients. Its clinical presentation is asymptomatic in half of the cases, in the other half there is pain, soft tissue edema, and decreased limb function. Radiographically it is accompanied by osteolysis, osteosclerosis, cystic lesions and pathological fractures in advanced stages. A final diagnosis is made by tissue biopsy, finding non-caseating granulomatous process accompanied by Langhans giant cells. The main indication of medical management is the control of symptoms, associated with an improvement in the functioning of the affected limb and quality of life of the patient. The case is presented of a patient with digital sarcoidosis with classic radiographic pattern with no other extra-skeletal involvement.

Keywords : Sarcoidosis; Musculoskeletal disease; Bones; Granuloma.

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