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Revista Médica de Risaralda
Print version ISSN 0122-0667
Abstract
TREJOS-RAMIREZ, Carlos Andrés; RODRIGUEZ-ORTIZ, Jorge Augusto; MORTIMER-ARREAZA, Graterol and RAMIREZ PESCADOR, Fabiana. Platelet distribution width as a marker for the development of severe preeclampsia. Revista médica Risaralda [online]. 2019, vol.25, n.2, pp.77-82. ISSN 0122-0667.
Introduction:
The pathophysiology of preeclampsia is not completely elucidated. Different platelet indices, including the platelet distribution width (PDW), could be used to predict the severity of this condition.
Objective:
To analyze the behavior of PDW in the severity development of preeclampsia in women treated in the maternal-fetal medicine unit of Hospital Simón Bolívar in Bogotá, Colombia.
Materials and methods:
This is an analytical cross-sectional study in 105 patients with hypertensive disorder associated with pregnancy, preeclampsia and severe preeclampsia. We analyzed the behavior of PDW in a population of hypertensive women with preeclampsia using a curve of analysis '' Receiver Operating Characteristic '' (ROC) to estimate the sensitivity, false positive rate, positive and negative likelihood ratio of the test as a marker of development of severity
Results:
PDW had a higher significant increase in patients where their disease progression developed severity characteristics. In the ROC curve, the area under the curve for PDW as a predictor of severity in preeclampsia was 0.68.
Conclusion:
PDW is a platelet index that increased significantly in women with preeclampsia with severity characteristics. PDW could be a marker for the prediction of severity of preeclampsia.
Keywords : pre-eclampsia; toxemia; blood platelets disorders..