Abstract

FIERRO, Luis F. et al. Diabetes after non-surgical treatment of a malignant insulinoma: Case report and literature review. rev.colomb.cancerol. [online]. 2020, vol.24, n.1, pp.30-36.  Epub May 11, 2020. ISSN 0123-9015.  https://doi.org/10.35509/01239015.138.

Pancreatic neuroendocrine tumors (TNEP) are a rare group of neoplasms, which can secrete peptide hormones causing various clinical syndromes, or be non-secretory, with symptoms secondary to invasion of neighboring or distant structures (1). The case of a 55-year-old patient with malignant insulinoma with extensive metastatic involvement, not operable, with persistent hypoglycemia refractory to treatment with diazoxide and prednisolone, who received management with chemotherapy and embolization of liver metastases, achieving the withdrawal of medications for the management of hypoglycemia and a tumor response of stable disease in the comparison of images during the 12-month follow-up. During the 15th cycle of chemotherapy, he presented symptoms of hyperglycemia with HbA1c in 12%, with which diabetes de novo mellitus was diagnosed and insulin management was initiated.

Keywords : Myocutaneous Flap; Mastectomy; Mammaplasty.

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