Abstract

DE LAS SALAS, Roxana et al. Suspected hypersensitivity probably related to the use of morphine: A case report. Rev. salud pública [online]. 2023, vol.25, n.2, 13.  Epub Mar 01, 2023. ISSN 0124-0064.  https://doi.org/10.15446/rsap.v25n2.103211.

The case of a 46-year-old male patient is presented. He was admitted to the emergency department with a clinical picture of oppressive chest pain of 10/10 intensity on the pain analog scale, which had been evolving for one hour. After evaluation and based on electrocardiographic and laboratory findings, the patient was diagnosed with acute myocardial infarction with st elevation. Additionally, aortic dissection and hypertensive emergency with end-organ damage to the heart were suspected due to intense precordial pain and blood pressure readings of 230/120 mmHg. As part of the therapeutic approach, 3 mg of intravenous morphine diluted in 10 ml of 0.9 % saline solution were administered. Following administration, the patient exhibited suspected hypersensitivity. Therefore, a suspected adverse event assessment was performed using the Naranjo algorithm, and it was established that the effects of morphine were plausible (category probable).

Keywords : Morphine; drug-related side effects and adverse reactions; hypersensitivity; pharmacovigilance (source; MeSH, NLM).

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )