Services on Demand
Journal
Article
Indicators
- Cited by SciELO
- Access statistics
Related links
- Cited by Google
- Similars in SciELO
- Similars in Google
Share
Universidad y Salud
Print version ISSN 0124-7107On-line version ISSN 2389-7066
Abstract
QUENAN, Yoccner Edilson and OSORIO, José Henry. Relationship between obesity, adipocytokines and osteoarthritis: Review. Univ. Salud [online]. 2017, vol.19, n.3, pp.410-418. ISSN 0124-7107. https://doi.org/10.22267/rus.171903.103.
Introduction:
Some adipocytokines expressed by osteoblasts, chondrocytes and synoviocytes are responsible of the inflammation and degradation of the extracellular matrix in the joints, which generates osteoarthritis.
Objective:
To review the current state of knowledge around the relationship between obesity, adipocytokines and osteoarthritis.
Materials and methods:
An electronic search was carried out in the databases of BBCS-LILACS, PubMed, IB-PsycINFO, IB-SSCI, IB-SciELO, Scopus and Science Direct in English and Spanish, without limiting the search by date. Clinical trials, meta-analyses, reviews, case reports and classic articles related to obesity and its implications were included as well as osteoarthritis, adipocytokines, adipose tissue and joint inflammation.
Results:
822 articles were found; however, 78 documents met the selection criteria for the relevance of the information. This work was divided into three sections: Osteoarthritis and obesity, osteoarthritis and inflammation and osteoarthritis and adipocytokines.
Conclusion:
Nowadays, obesity is associated with the development of osteoarthritis, as it triggers a series of inflammatory processes mediated by the adipocytokines. Several studies recommend the development of clinical research to understand the behavior of adipocytokines before and during the development of osteoarthritis.
Keywords : obesity; inflammation; metabolism; adipose tissue; osteoarthritis.