Abstract

JIMENEZ-ACOSTA, Donys; MARQUEZ-VIZCAINO, Rita; DE LA ROSA-TORRES, Catalino  and  PABON-VIDAL, Adriana. Antiplasmodial and antibacterial in vitro activity from extracts the bark of Erythrina fusca Lour. (Fabaceae). Actu Biol [online]. 2016, vol.38, n.105, pp.139-144. ISSN 0304-3584.  https://doi.org/10.17533/udea.acbi.v38n105a01.

The phytochemical screening of ethanol extract of the dried bark of Erythrina fusca Lour. (Fabaceae), determined the presence of alkaloids, flavonoids, terpenes, and quinones. The chloroform and acetone fractions of ethanol extract of the dried bark of E. fusca, presented a moderate antiplasmodial activity in NF54 and FCB-2 strains of Plasmodium falciparum with IC₅₀ of 12.95, 18.02, 16.60, and 28.36 μg/ml, and a percentages inhibition of maximum average 70.72, 69.74, 87.07, and 85.73%, respectively. The ethanol extract showed inhibition at the concentration of 20 mg/ml for the strain of Staphylococcus aureus and chloroform fraction at the same concentration on Bacillus subtilis, Pseudomona aeruginosa, and Staphylococcus aureus.

Keywords : Bacillus subtilis; Erythrina fusca; Plasmodium falciparum; Pseudomona aeruginosa; Staphylococcus aureus.

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