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Revista Colombiana de Cirugía
Print version ISSN 2011-7582On-line version ISSN 2619-6107
Abstract
ESPITIA, David; GARCIA-LOPEZ, Andrea; PATINO-JARAMILLO, Nasly and GIRON-LUQUE, Fernando. Long-term outcomes in kidney transplant patients with expanded criteria donors: 10-year experience. rev. colomb. cir. [online]. 2022, vol.37, n.2, pp.214-225. Epub Apr 30, 2022. ISSN 2011-7582. https://doi.org/10.30944/20117582.1052.
Introduction.
Kidney transplantation is the treatment of choice for chronic kidney disease. Due to the gap with donor availability, the use of expanded criteria is an option that seeks to improve the global donation rate. The objective of this study was to compare the survival of the graft and the transplanted patient with an expanded criteria donor versus the standard donor.
Methods.
Retrospective cohort of 1002 kidney transplant patients where survival of the kidney graft and the recipient was determined at 10 years after transplantation. The survival of the kidney graft and the recipient were estimated by the Kaplan-Meier method. A Cox regression was performed by fitting the multivariate model.
Results.
The analysis included 1002 recipients with 18.8% (n=189) corresponding to the use of an expanded criteria donor. The expanded criteria donor kidney transplant group had lower patient (48.1% versus 63.8%) and graft (63.3% versus 74.7%) survival compared to the donor kidney transplant group with standard criteria at 10 years post-transplant. The association of kidney transplantation with expanded criteria donor and death or loss of the kidney graft were not significant when the variables were adjusted in the multivariate model.
Conclusion.
Kidney transplantation with an expanded criteria donor has a lower recipient and graft survival compared to the standard kidney transplant group. There were no statistically significant differences in expanded criteria donor kidney transplantation versus kidney graft loss or death.
Keywords : kidney transplant; donor selection; transplant donor site; tissue and organ procurement; graft rejection; graft survival.