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Revista Colombiana de Nefrología
On-line version ISSN 2500-5006
Abstract
CASTANEDA ESPINOSA, Laura et al. Prevalence of chronic kidney disease in a population with type 2 diabetes of a cardiovascular risk program. Rev. colom. nefrol. [online]. 2020, vol.7, n.2, pp.55-66. Epub Apr 23, 2021. ISSN 2500-5006. https://doi.org/10.22265/acnef.7.2.481.
Introduction:
In Colombia, the prevalence of type 2 diabetes mellitus (DM2) is 7-9%, this being the main cause of end-stage renal disease in the world4. In the municipality of Armenia, the prevalence of the population suffering from DM2 with chronic kidney disease (CKD) and the risk factors related to its development are unknown.
Objective:
To determine the prevalence and risk factors of developing chronic kidney disease (CKD) in a population with type 2 diabetes, consultants to a cardiovascular risk program of an IPS of Armenia, Colombia, during the year 2017.
Methods:
Descriptive cross-sectional study with 232 patients. The variables were described by measures of central tendency and 95 % confidence intervals, ANOVA and Chi square tests were performed for the numerical and categorical variables respectively, multiple regression and logistic regression, with a value of P <0.05.
Results:
The prevalence of diabetes was 34.14 % and CKD varies between 22.41-38.79 % according to the equation used. 69.83 % are in normoalbuminuria, 25 % in microalbuminuria and 5.17 % in macroalbuminuria. The risk factors identified for CKD were: age (Cockcroft-Gault and CKD-EPI p <0.001; MDRD p = 0.012), abdominal perimeter (Cockcroft-gault p <0.001; MDRD p = 0.028; CKD-EPI p = 0.011), creatinine level (Cockcroft-gault, MDRD, CKD-EPI p <0.001) and sedentary lifestyle (Cockcroft-gault p = 0.046). The most adequate equations for early identification of CKD in this population are CKD-EPI (R2 = 85.74 %) and Cockcroft-gault (R2 = 85.43 %), with a prognostic value of 95.68 % and 93, 96 % respectively.
Conclusion:
The prevalence of CKD varies between 22.41 % and 38.79 %, depending on the equation used. The risk factors for developing CKD are age, creatinine level, abdominal perimeter and sedentary lifestyle. It is proposed that for this population the Cockcroft-Gault and CKD-EPI equations are the most adequate to identify CKD.
Keywords : type 2 diabetes mellitus; chronic kidney disease; prevalence; risk factors; glomerular filtration rate; creatinine (MeSH).