Abstract

PIAMO, Alberto; GARCIA, Mayra; ROMERO, Dayset  and  FERRER, Daisy. Healing of a chronic ulcer of the lower limb of venous origin with fresh human amniochorionic membrane allograft. Biomed. [online]. 2022, vol.42, suppl.1, pp.17-25.  Epub May 01, 2022. ISSN 0120-4157.  https://doi.org/10.7705/biomedica.6319.

In its fresh state, the amniochorionic membrane contains various multipotential cells, growth factors, and extracellular matrix proteins that contribute to the healing of chronic vascular ulcers. To demonstrate its effectiveness, a fresh human placental membrane allograft was applied to a chronic venous ulcer in the lower limb of an 89-year-old female patient with a 12 x 10 cm ulcerated lesion of 40 years of evolution in the malleolar area of her left lower limb. Sixty days after the graft, the ulcer was healed in 100% of its surface and a light pink scar on the edges indicated possible pigmentation. Fresh human amniochorionic membrane allograft is a therapeutic alternative for the healing of refractory chronic vascular ulcers of the lower extremities.

Keywords : Varicose ulcer; allografts; amnion..

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