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Print version ISSN 0121-4500
Abstract
MARTINEZ GUTIERREZ, Alfonsina del Cristo and CHAVEZ VIVAS, Mónica. Clinical and therapeutic characterization of patients with pulmonary tuberculosis in Cali. av.enferm. [online]. 2017, vol.35, n.3, pp.324-332. ISSN 0121-4500. https://doi.org/10.15446/av.enferm.v35n3.62733.
Objective:
To ascertain clinical, socio-demographic and pharmacological characteristics of patients with pulmonary tuberculosis.
Methodology:
This is a descriptive, retrospective, and cross-sectional study conducted on a sample of 157 patients. Data were extracted from the Secretaría Municipal de Salud Pública database of the city of Cali during 2013. Correlations among variables was identified using the Chi-Square Test of Independence and the IBM spss Statistics 22.0.
Results:
62.4% of the study subjects were young men and 72%, came from low socio-economic levels. 9.2% of patients developed drug-resistant pulmonary tuberculosis (p = 0.0231). Resistance to isoniazid was 94.2%; to rifampicin, 78.8%; to pyrazinamide, 21.2%; to ethambutol, 25%; to streptomycin, 48.1%. Malnourished patients and drug/alcohol addicts were more resistant to antituberculosis therapy. 19.2% of patients were drug-resistant pulmonary tuberculosis and drug/ alcohol addicts; 15.4%, had diabetes; and 13.4%, were co-infected with human immunodeficiency virus (HIV).
Conclusions:
The higher proportion of males with tuberculosis might be influenced by an exposure to the infective agent, since this group is the most working population. A higher prevalence of strains that are multi-drug-resistant to first-line drugs was found in patients from low socioeconomic levels, belonging to marginalized groups, and with risk factors, such as malnutrition, and alcohol/ psychoactive substances abuse.
Keywords : Tuberculosis, Pulmonary; Mycobacterium Tuberculosis; Drug Resistance, Microbial; Health Services Research (source: DeCS, BIREME).