Abstract

MADIEDO CLAVIJO, Cristina Nohora  and  PEREA SOLANO, Dario José. Advances in the molecular basis of anaesthesiology. Rev. colomb. anestesiol. [online]. 2009, vol.37, n.2, pp.141-151. ISSN 0120-3347.

Although the first anaesthetic was given more than a century ago, the subsequent emergence of several anaesthetic drugs enabled several components involved in its administration to be identified. Only during the past 30 years has the molecular basis for anaesthetics- mechanisms of action become known (especially undergoing vertiginous progress during the last decade). It is of vital importance for an anaesthesiologist to know the molecular basis of anaesthesia and ensure complete comprehension of anaesthetics- effects, interactions and toxicity. Such knowledge will have an impact on the suitable administration of available drugs and the creation of new ones having more specific action.

Keywords : molecular biology; anaesthesia; receptor; immobility; amnesia; GABA.

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