Objective:

Blockchain technology, including its main features, is introduced. The P6 medicine model for patient-centered care is also shown, and finally, the applications of Blockchain technology as a security and interoperability layer for IoT medical devices and hospital information systems is presented.

Methodology:

A review of the publications registered in the bibliographic collections of IEEE Xplore and Scopus was carried out, with a filter on publications focused on Blockchain, IoT and health, in addition. The analysis of the articles focused on the approach of a functional congruence scenario of these three elements.

Results:

Blockchain and IoT applications for comprehensive health care are presented, with an outline of the interaction of Blockchain technology between hospital information systems and IoT medical sensors to create the necessary conditions in the implementation of the P6 medicine.

Conclusions:

The application of Blockchain technology was identified as the necessary interoperability layer to allow interoperability between hospital information systems, research centers, patients, doctors and the interested community, to generate a reliable environment for the flow of information among the actors that allow it, and will enhance streamline research and healthcare processes.