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Universidad y Salud
Print version ISSN 0124-7107On-line version ISSN 2389-7066
Abstract
RODRIGUEZ-VELASQUEZ, Javier; PRIETO, Signed and RAMIREZ-LOPEZ, Leonardo. Adult dynamic heart evaluated by the proportions of entropy. Univ. Salud [online]. 2017, vol.19, n.2, pp.248-257. ISSN 0124-7107. https://doi.org/10.22267/rus.171902.87.
Introduction:
A new mathematical methodology of clinical application has been developed from the theory of dynamic systems, together with the theory of probability and the concept of entropy.
Objective:
To apply the methodology previously developed to evaluate the heart dynamics of adult through the probability and proportions of entropy of the attractor.
Materials and methods:
A blind study was developed taking as Gold Standard the conventional diagnosis issued by an expert with 480 Holter, 30 normal dynamics and 450 with different pathologies. For each Holter, a numerical attractor was generated by quantifying the probability of appearance of consecutive pairs of cardiac frequencies, subsequently evaluating entropy, S/K ratio and proportions for each dynamic for at least 18 hours. The values of sensitivity, specificity and Kappa coefficient were found.
Results:
The applied methodology allowed to differentiate quantitatively normality of disease, finding the values of the proportions in the established ranges. The sensitivity and specificity values were 100%, and Kappa coefficient was 1.
Conclusion:
It is possible to diagnose cardiac dynamics for at least 18 hours based on the probability distributions of the appearance of consecutive pairs of cardiac frequencies and their entropy.
Keywords : Ambulatory electrocardiography; mathematics; nonlinear dynamics; heart rate.