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Acta Medica Colombiana
Print version ISSN 0120-2448
Abstract
CORONADO, Carlos Yesid and ECHEVERRY, Ivonne. Clinicopathological description of glomerular diseases. Acta Med Colomb [online]. 2016, vol.41, n.2, pp.125-129. ISSN 0120-2448.
Objective:
to describe the clinical and histopathological findings of glomerular diseases diagnosed by biopsy.
Material and Methods:
a descriptive study of glomerular disease according to the clinical involvement and histopathologic findings obtained by renal biopsy in patients aged 14 years or older treated at the Renal Unit of Tolima in Ibague between 1999 and 2014. The collection data was conducted by reviewing medical records and reports of renal biopsy. The clinical presentation was classified as: nephrotic proteinuria, non-nephrotic proteinuria, nephritic syndrome, monosymptomatic hematuria, decreased renal function, acute renal failure.
Results:
one hundred eighty-one patients met the inclusion criteria. Median creatinine was 1.29 mg / dl. All biopsies were studied with immunohistochemistry and 97.24% was studied using electron microscopy. The average age was 36.93 ± 13.87 years. The most common secondary nephropathy was lupus. The most common primary cause of nephrotic syndrome was membranous glomerulonephritis and the most common primary cause of non-nephrotic proteinuria was focal and segmental glomerulosclerosis.
Conclusions:
the most common cause of secondary glomerulopathy was lupus, and the most common primary glomerular diseases were membranous glomerulonephritis and focal and segmental glomerulosclerosis, similar to other studies. IgA nephropathy was rare (5.52%). (Acta Med Colomb 2016; 41: 125-129).
Keywords : biopsy; epidemiology; glomerulonephritis; hispanic americans.