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Colombian Journal of Anestesiology
Print version ISSN 0120-3347
Abstract
RODRIGUEZ, René Fernando et al. Determinación de la eficacia analgésica de los bloqueos del ganglio estrellado en el alivio del dolor mediado por el sistema nervioso simpático, en pacientes con síndrome doloroso regional complejo del miembro superior. Rev. colomb. anestesiol. [online]. 2005, vol.33, n.3, pp.153-159. ISSN 0120-3347.
To determine the analgesic efficacy of the stellate ganglion blockade (SGB) in the alleviation of pain mediated by the sympathetic nervous system in patients with Complex Regional Pain Syndrome, a randomized, double-blinded controlled clinical trial was conducted. Forty-one patients were randomly assigned to an intervention group which was treated with a series of SGB, physical therapy and pharmacological treatment; and 41 to a control group which was treated with physical therapy and the same pharmacological treatment. Hazard ratio, Kaplan-Meier and Cox proportional hazards modeling were used to evaluate outcome and determine association with predictor variables. At the end of the two months of follow-up efficacy in the control group was 46%, RAR 17% and NNT 6; the Kaplan-Meier estimate of the cumulative free pain rate was 80% in the intervention group and 63% in the control group. The overall failure rate was higher in the control group: hazard ratio = 2.7 (95% CI, 1.1 to 6.7).
Keywords : Complex regional pain syndrome; Stellate ganglion block; Sumpathetic pain.