Abstract

QUINTERO-CASTELLANOS, Manuel. Pregabalin-induced liver injury - Case report. Rev. colomb. anestesiol. [online]. 2017, vol.45, n.4, pp.349-352. ISSN 0120-3347.

The first case of idiopathic pregabalin-induced toxicity in Latin America is reported in a patient with radicular pain secondary to lumbar spinal stenosis, who presented with jaundice and elevation of liver enzymes, associated with the use of pregabalin. A diagnosis of drug-induced liver injury was made. Liver function was normalized once the drug was discontinued without any sequelae. It is important to be aware of the potential hepatic toxic effects of pregabalin, despite the fact that the drug shows no evidence of liver metabolism and liver toxicity is very unusual. The liver injury mostly resolves upon pregabalin removal.

Keywords : Low back pain; Pregabalin; Jaundice; Liver failure; Toxicity.

        · abstract in Spanish     · text in English | Spanish     · English ( pdf ) | Spanish ( pdf )