Abstract

DE LAS SALAS-MARTINEZ, Roxana Patricia  and  VILLARREAL-CANTILLO, Elizabeth. Interactions in the use of antacids, mucosal protective and gastric antisecretory drugs. Salud, Barranquilla [online]. 2013, vol.29, n.3, pp.441-457. ISSN 0120-5552.

Due to the frequency of the association of drugs for the treatment of various diseases, it is necessary to consider situations arising from the simultaneous administration of drugs. Nowadays, is recognized the existence of a variety of drug interactions that occur by different mechanisms. Therefore, it is important that Nursing Professionals perform continuous monitoring to assess the therapeutic goals set, in order to prevent Adverse Drug Reactions and/or toxicity and Therapeutic Failure. For that reason, the aim of this reviewing is to present the major drug interactions that occur with the administration of antacids, mucosal protective agents, gastric antisecretory and its consequences. The compromise of Nursing and Health Care Professionals, should go towards empowerment of knowledge of this topic, in order to deal with responsibility, the monitoring of therapeutic safety and effectiveness, recognizing that there are many unknown pharmacological interactions that will occur as soon as the new active ingredient appears. At the same time, it is important to consider the clinical impact that produces the use of antacids, gastric mucosal protective and antisecretory drugs.

Keywords : drug interactions; pharmacology; nursing; anti-ulcer agents.

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