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Revista Salud Uninorte
Print version ISSN 0120-5552On-line version ISSN 2011-7531
Abstract
PANESSO-VALENCIA, LAURA JULIANA; CELIS-GIRALDO, DANIEL and NIETO-CARDENAS, OLGA ALICIA. 25-hydroxyvitamin D levels and cardiovascular risk in a university student population of Armenia-Colombia. Salud, Barranquilla [online]. 2020, vol.36, n.3, pp.516-531. Epub Oct 22, 2021. ISSN 0120-5552. https://doi.org/10.14482/sun.36.3.616.1.
Objective:
To describe the correlation between 25-hydroxyvitamin D levels and cardiovascular risk in Armenia-Colombia.
Materials and methods:
During 2017-2018 was conducted a descriptive cross-sectional study. The cardiovascular risk was determined by Framingham, Framingham Colombia and OMS/ISH scores. Lipids, insulin, cytokines and 25-hydroxyvitamin D were measured. Then Anova test, multiple regression and Chi-square test were performed. Values below p<0.05 were considered statistically significant.
Results:
The average age was 21.05 years old (CI95: 20,62 - 21,48) and the average vitamin D levels was 27.7 ng/ml (CI95: 26,52 - 28,88). Statistically significant differences were also found by sex (p=0,009), deficiency and insufficient vitamin D were more frequent in women. The Framingham score was -4.02±3.7. There is a relation between the explained variation (R2) of the score with cholesterol (p<0.001), HDL cholesterol (p<0.001) and vitamin D (p=0.039). Framingham percentage is related to age (p=0.031), abdominal perimeter (p=0.005), interferon-Y (p<0.001) and interleukin-6 (p=0.050).
Conclusion:
Vitamin D deficiency and insufficiency were prevalent conditions. The explained variation of the Framingham score model is associated with cholesterol, HDL cholesterol and vitamin D. And the Framingham percentage with age, abdominal perimeter, interferon-Y and interleukin-6.
Keywords : vitamin D; calcitriol; deficiency; cardiovascular diseases; risk factors.