Services on Demand
Journal
Article
Indicators
Cited by SciELO
Access statistics
Related links
Cited by Google
Similars in SciELO
Similars in Google
Share
Revista Colombiana de Cardiología
Print version ISSN 0120-5633
Abstract
MIRANDA-ARBOLEDA, Andrés F. et al. Predictors of mortality in patients with coronary artery disease and involvement of the left main artery. Rev. Colomb. Cardiol. [online]. 2022, vol.29, n.6, pp.629-639. Epub Dec 27, 2022. ISSN 0120-5633. https://doi.org/10.24875/rccar.22000023.
Introduction:
involvement of the unprotected left main coronary artery (TPInp) in patients with coronary artery disease (CAD) leads to a high risk of cardiovascular events. Coronary artery bypass grafting (CABG) has been the standard of management; however, recent studies propose percutaneous coronary intervention (PCI) as an alternative treatment.
Objective:
to evaluate the in-hospital and follow-up outcomes of patients with compromised TPInp.
Method:
retrospective multicenter observational cohort study, we evaluated patients with CAD and TPI involvement. Death from any cause, nonfatal myocardial infarction, stroke, reoperation, and/or hospital readmission were assessed as a composite endpoint and individually during hospitaliza- tion and follow-up time.
Results:
82 patients were included, mean age 71 ± 9.9 years; 35 received PCI, 31 CABG, and 16 medical management (MM). In-hospital mortality was 16%. In the mean follow-up of 12.3 months, mortality was 20%, rein- farction 6% and hospital readmission 4%. The incidence rate of death was 5.19 per 10,000 people/day for MM, 2.3 per 10,000 people/day for PCI, and 1.06 per 10,000 people/day for CABG; at follow-up, mortality was higher in the PCI group (HR 3.6; 95%CI 1.13-11.9; p = 0.02). Elevated heart rate on admission was associated with higher mortality (p < 0.05).
Conclusion:
TPInp involvement is associated with a high risk of death and presents with complex coronary anatomy.
Keywords : Left main coronary artery disease; Percutaneous coronary intervention; Coronary artery bypass graft surgery.