Abstract

COLONIA GARCIA, ADRIANA  and  DUQUE DUQUE, ANDRÉS. Effectiveness of the treatment of periodontal disease on markers of cardiovascular risk. CES Med. [online]. 2011, vol.25, n.2, pp.181-192. ISSN 0120-8705.

The main risk factors associated with cardiovascular events include age, gender, hypertension, diabetes mellitus, smoking, low high-density lipoprotein, genetics, stress, obesity and physical inactivity. There are no identified risk factors still to explain the cardiovascular model. Periodontal disease has emerged in recent decades as a possible risk factor for developing cardiovascular events. A systematic review presents a relative risk (RR) of 1.19 (95% CI, 1.08 to 1.32) for the association between periodontal disease and cardiovascular disease and 2.85 (95% CI, 1, 78 to 4.56) for stroke. Periodontitis has a systemic effect to produce large amounts of inflammatory mediators (hyper secretion of cytokines IL-1, IL-6, IL-8, prostaglandin E2, CRP and fibrinogen). We conducted a narrative review of the impact of mechanical and drug periodontal therapy on endothelial function and decreased pro-inflammatory substances cardiovascular risk markers such as CRP and serum IL-6. It is concluded that periodontal disease is a modifiable risk factor, which could be prevented and treated with low-risk procedures, so their treatment can be an integral component of preventive cardiology

Keywords : Periodontal diseases; Cardiovascular diseases; Biological markers; Risk factors.

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